The new way (without the “Run” choice inside NPP) is much too slow and clunky. This is a most useful setup for website editing since I can quickly see how my html looks in different browsers. $(NPP_DIRECTORY) otepad++.exe $(CURRENT_WORD) -nosession -multiInst

$(NPP_DIRECTORY) otepad++.exe $(CURRENT_WORD) This is how my shortcuts.xml file looks now: I could find all the bits & pieces, but it never would have occurred to me to edit the shortcuts file as you described. I could never have figured it out on my own. Yes, your hints, plus Meta Chuh’s, did the trick. That is because upon closing, NPP can update the file itself if anything during the current session dictates updating information within that, or other configuration files. So you can highlight the block of code then use this shortcut.

The default for a block comment is CTRL + SHIFT + Q. You can go to Settings > Shortcut Mapper to change this to match your preference.

Make sure that if you are editing this file with Notepad++ (NPP), it is the ONLY step you do in a NPP session. In notepad++ I believe that the shortcut is CTRL + Q for commenting the code.

Commenting code in notepad++ shortcut